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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CACNA1H All Species: 7.27
Human Site: S2287 Identified Species: 26.67
UniProt: O95180 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95180 NP_001005407.1 2353 259163 S2287 P F L D G S H S V T P E S R A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537016 2449 267905 G2383 L F L D S G H G V A P E P R A
Cat Felis silvestris
Mouse Mus musculus O88427 2365 261928 S2300 C F L D S D Q S V T P E P R V
Rat Rattus norvegicus Q9EQ60 2359 261094 S2294 C F L D S D Q S V T P E P R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414830 2380 267842 S2316 E Q S D G G G S L S S L S D L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q2XVR3 1829 207718 N1769 E T R P M R P N S Q P P K P S
Tiger Blowfish Takifugu rubipres Q2XVR6 1719 196461 G1659 E K A P E T T G L L C K Q F S
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 79.9 N.A. 84.5 84.9 N.A. N.A. 69.7 N.A. 23.7 21.7 N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. 84.2 N.A. 88.2 88.5 N.A. N.A. 78.9 N.A. 40.2 38.7 N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. 60 N.A. 60 60 N.A. N.A. 26.6 N.A. 6.6 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. 60 N.A. 60 60 N.A. N.A. 40 N.A. 20 26.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 0 0 0 0 0 0 15 0 0 0 0 29 % A
% Cys: 29 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % C
% Asp: 0 0 0 72 0 29 0 0 0 0 0 0 0 15 0 % D
% Glu: 43 0 0 0 15 0 0 0 0 0 0 58 0 0 0 % E
% Phe: 0 58 0 0 0 0 0 0 0 0 0 0 0 15 0 % F
% Gly: 0 0 0 0 29 29 15 29 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 29 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 15 0 0 0 0 0 0 0 0 0 15 15 0 0 % K
% Leu: 15 0 58 0 0 0 0 0 29 15 0 15 0 0 15 % L
% Met: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % N
% Pro: 15 0 0 29 0 0 15 0 0 0 72 15 43 15 0 % P
% Gln: 0 15 0 0 0 0 29 0 0 15 0 0 15 0 0 % Q
% Arg: 0 0 15 0 0 15 0 0 0 0 0 0 0 58 0 % R
% Ser: 0 0 15 0 43 15 0 58 15 15 15 0 29 0 29 % S
% Thr: 0 15 0 0 0 15 15 0 0 43 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 58 0 0 0 0 0 29 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _